Clinical Studies

Demonstrating the Efficacy of Prone
Therapy in ARDS Patients

The following clinical studies demonstrate the efficacy of manual and automated prone therapy in Acute Respiratory Distress Syndrome (ARDS) patients. Additional studies are available upon request.

Important Message for Patients

Continuous lateral rotation therapy to prevent ventilator-associated pneumonia*.

Staudinger T, Bojic A, Holzinger U, et al. Critical Care Medicine. 2010;38(2).

New study published in Critical Care Medicine demonstrates that Kinetic Therapy ≥ 40° reduces VAP, length of stay and atelectasis.

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Ventilatory management of acute respiratory distress syndrome: a consensus of two

Marini JJ, Gattinoni L. Critical Care Medicine. 2004;32(1):250-255. (Study utilized manual proning)

This article provides a practical guideline for ventilator management of ARDS with a special emphasis on preventing ventilator induced lung injury. On page 253, the authors provide guidance about when to prone patients with ARDS. “We place in the prone position those requiring >10 cm H₂0 PEEP at FiO₂ of ≥0.6 to maintain oxygen saturation at ≥90%, unless there is a clear contraindication or the patient is rapidly improving.”

Prone ventilation in trauma or surgical patients with acute lung
injury and adult respiratory distress syndrome: is it beneficial?

Davis JW, Lemaster DM, Moore EC, et al. J Trauma. 2007;62(5):1201-1206. (Study utilized RotoProne™ Therapy)

This article compares the effectiveness of supine versus prone kinetic therapy in mechanically ventilated trauma and surgical patients with acute lung injury (ALI) and adult respiratory distress syndrome (ARDS). The conclusions of this article show that patients with ALI/ARDS who received prone kinetic therapy had greater improvement in oxygenation (P/F ratio increase), a reduction in the number of ventilator days, lower mortality, and less pulmonary-related mortality than did supine positioned patients.

Prone positioning: improving oxygenation
in patients with ARDS

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